Towards Point-of-Care Diagnosis of Pulmonary Tuberculosis and Drug Susceptibility Testing by Whole Genome Sequencing of DNA Isolated from Sputum

Preliminary screening of pulmonary tuberculosis (TB) in India still relies on sputum microscopy, which has low sensitivity leading to high rate of false negatives. Moreover, conventional phenotypic drug susceptibility testing (DST) is conducted over a period of weeks leading to delays in correct tre...

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Bibliographic Details
Main Authors: Kayzad S. Nilgiriwala, Louise Pankhurst, Ali Vaughan, Zamin Iqbal, Derrick Crook, Anirvan Chatterjee, Nerges Mistry
Format: Article
Language:English
Published: Science Planet Inc. 2017-12-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a251.pdf