Moderate physical exercise improves lymphocyte function in melanoma-bearing mice on a high-fat diet

Moderate physical exercise improves lymphocyte function in melanoma-bearing mice on a high-fat diet

Abstract Background Obesity can lead to a chronic systemic inflammatory state that increases the risk of cancer development. Therefore, this study aimed to evaluate the alterations in tumor non-infiltrated lymphocytes function and melanoma growth in animals maintained on a high-fat diet and/or moder...

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Main Authors: Cesar Miguel Momesso dos Santos, Vinicius Leonardo Sousa Diniz, André Luis Lacerda Bachi, Laiane Cristina dos Santos de Oliveira, Tamara Ghazal, Maria Elizabeth Pereira Passos, Heloisa Helena de Oliveira, Gilson Murata, Laureane Nunes Masi, Amanda Roque Martins, Adriana Cristina Levada-Pires, Rui Curi, Sandro Massao Hirabara, Donald F. Sellitti, Tania Cristina Pithon-Curi, Renata Gorjão
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Nutrition & Metabolism
Subjects:
Cytokines
Th1 lymphocytes
B16F10 cells
Cancer
Obesity
Immune function
Online Access:http://link.springer.com/article/10.1186/s12986-019-0394-z

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