Effect of treatment with vitamin E and sodium selenate in some biochemical variables in the blood of male adult rats and treated with cadmium chloride

• Main Author: Afrah Jasem
• Format: Article
• Language: Arabic
• Published: College of Education for Pure Sciences 1970-01-01
• Series: مجلة التربية والعلم
• Subjects: vitamin e; sodium selenate; biochemical variables; blood of male adult rats; cadmium chloride
• Online Access: https://edusj.mosuljournals.com/article_58931_9f9004eefdc617a7cc95c3a767fa7f9f.pdf
• ISSN: 1812-125X; 2664-2530

Abstract<br /> This study designed to determine the effect of vitamine E and sodium selenite on the level of some biochemical parameters in serum of male rats exposed to oxidative stress induced by cadmium chloride.<br /> The study showed that treatment with cadmium chloride (25 mg/liter of drinking water) for 30 days caused a significant decrease in the body weight, with a significant increase in the level of glucose, cholesterol and triglycerides. Treatment of rats exposed to oxidative stress induced by cadmium chloride with vitamin E (500 mg/kg body weight) for 30 days show a non significant change in the body weight, but there was a significant increase in the level of glucose, cholesterol and triglycerides. Moreover treated rats exposed to oxidative stress induced by cadmium chloride (25 mg/liter drinking water) together with sodium selenite (0.5 mg/kg diet) for 30 days showed a non significant changes in body weight and the level of triglyceride, but a significant decrease in levels of glucose & cholesterol. Treatment with vitamin E together with sodium selenite to rats exposed to oxidative stress induced by cadmium chloride for 30 days showed a significant decrease in the level of glucose, cholesterol and triglycerides. <br /> It was concluded that administration of vitamin E with sodium selenite as antioxidants produced a significant decrease in glucose, cholesterol and triglycerides levels in rats exposed to oxidative stress induced by cadmium chloride.