Antinociceptive and antipyretic activities of Amaranthus viridis Linn. in different experimental models

• Main Authors: Kumar Ashok B.S., Lakshman K., Jayaveera K.N., Shekar Sheshadri D., Vivek C.
• Format: Article
• Language: English
• Published: University of Belgrade, University of Novi Sad 2010-01-01
• Series: Archives of Biological Sciences
• Subjects: Amaranthus viridis; antinociceptive activity; acetic acid writhing test; hot plate test; antipyretic activity
• Online Access: http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641002397K.pdf
• ISSN: 0354-4664

The methanolic extract of the whole plant extract of Amaranthus viridis L (MEAV) was screened for antinociceptive activity using the acetic acid writhing test, hot plate test and tail immersion test in mice and for antipyretic activity using the yeast-induced pyrexia method in rats, at doses of 200 and 400 mg/kg body weight. Significant (p<0.01) dose-dependent antinociceptive and antipyretic properties were observed with 200 and 400 mg/kg.