Next generation plasma proteome profiling to monitor health and disease

Next generation plasma proteome profiling to monitor health and disease

The proximity extension assay (PEA) is a popular tool to measure plasma protein levels. Here, the authors extend the proteome coverage of PEA by combining it with next-generation sequencing, enabling the analysis of nearly 1500 proteins from minute amounts of plasma.

Bibliographic Details
Main Authors: Wen Zhong, Fredrik Edfors, Anders Gummesson, Göran Bergström, Linn Fagerberg, Mathias Uhlén
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22767-z
Description
Summary:The proximity extension assay (PEA) is a popular tool to measure plasma protein levels. Here, the authors extend the proteome coverage of PEA by combining it with next-generation sequencing, enabling the analysis of nearly 1500 proteins from minute amounts of plasma.
ISSN:2041-1723

Similar Items