Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side

Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side

Abstract Oxidative stress is related to ageing and degenerative diseases, including cancer. However, a moderate amount of reactive oxygen species (ROS) is required for the regulation of cellular signalling and gene expression. A low level of ROS is important for maintaining quiescence and the differ...

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Bibliographic Details
Main Authors: Rodrigo Prieto-Bermejo, Marta Romo-González, Alejandro Pérez-Fernández, Carla Ijurko, Ángel Hernández-Hernández
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Reactive oxygen species (ROS)
Redox signalling
Oxidative stress
Haematopoietic stem cells (HSCs)
Leukaemia
NADPH oxidase (Nox)
Online Access:http://link.springer.com/article/10.1186/s13046-018-0797-0

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