Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

One puzzling observation in patients affected with Hutchinson-Gilford progeria syndrome (HGPS), who overall exhibit systemic and dramatic premature aging, is the absence of any conspicuous cognitive impairment. Recent studies based on induced pluripotent stem cells derived from HGPS patient cells h...

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Bibliographic Details
Main Authors: Xavier Nissan, Sophie Blondel, Claire Navarro, Yves Maury, Cécile Denis, Mathilde Girard, Cécile Martinat, Annachiara De Sandre-Giovannoli, Nicolas Levy, Marc Peschanski
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712001404

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