Effect of Shenmai injection on preventing the development of nitroglycerin-induced tolerance in rats.

Effect of Shenmai injection on preventing the development of nitroglycerin-induced tolerance in rats.

Long-term nitroglycerin (NTG) therapy causes tolerance to its effects attributing to increased oxidative stress and endothelial dysfunction. Shenmai injection (SMI), which is clinically used to treat cardiovascular diseases, consists of two herbal medicines, Ginseng Rubra and Ophiopogonjaponicas, an...

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Bibliographic Details
Main Authors: Qian Zhou, Yan Sun, Wangxiao Tan, Xiao Liu, Yuchen Qian, Xianghui Ma, Ting Wang, Xiaoying Wang, Xiumei Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5409518?pdf=render

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