Protein Kinase Cα and P-Type Ca2+ Channel CaV2.1 in Red Blood Cell Calcium Signalling

Protein Kinase Cα and P-Type Ca2+ Channel CaV2.1 in Red Blood Cell Calcium Signalling

Background/Aims: Protein kinase Cα (PKCα) is activated by an increase in cytosolic Ca2+ in red blood cells (RBCs). Previous work has suggested that PKCα directly stimulates the CaV2.1 channel, whereas other studies revealed that CaV2.1 is insensitive to activation by PKC. The aim of this study was t...

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Bibliographic Details
Main Authors: Lisa Wagner-Britz, Jue Wang, Lars Kaestner, Ingolf Bernhardt
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Phosphatidylserine
Protein kinase C
P-type Ca2+ channel
Flow cytometry
Fluorescence imaging
Red blood cells
Ca2+ content
Online Access:http://www.karger.com/Article/FullText/350106

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