Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.

Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.

<h4>Background</h4>Alterations in the stem cell niche are likely to contribute to tumorigenesis; however, the concept of niche promoted benign tumor growth remains to be explored. Here we use keloid, an exuberant fibroproliferative dermal growth unique to human skin, as a model to charac...

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Bibliographic Details
Main Authors: Qunzhou Zhang, Takayoshi Yamaza, A Paul Kelly, Shihong Shi, Songlin Wang, Jimmy Brown, Lina Wang, Samuel W French, Songtao Shi, Anh D Le
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19907660/?tool=EBI

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