Targeting Sonic Hedgehog Signaling by Compounds and Derivatives from Natural Products
Cancer stem cells (CSCs) are a major cause of cancer treatment failure, relapse, and drug resistance and are known to be responsible for cancer cell invasion and metastasis. The Sonic hedgehog (Shh) signaling pathway is crucial to embryonic development. Intriguingly, the aberrant activation of the S...
Main Authors: | Yu-Chuen Huang, K. S. Clifford Chao, Hui-Fen Liao, Yu-Jen Chen |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Evidence-Based Complementary and Alternative Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/748587 |
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