The non-peptidic part determines the internalization mechanism and intracellular trafficking of peptide amphiphiles.

BACKGROUND: Peptide amphiphiles (PAs) are a class of amphiphilic molecules able to self-assemble into nanomaterials that have shown efficient in vivo targeted delivery. Understanding the interactions of PAs with cells and the mechanisms of their internalization and intracellular trafficking is criti...

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Bibliographic Details
Main Authors: Dimitris Missirlis, Tambet Teesalu, Matthew Black, Matthew Tirrell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547919?pdf=render

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