Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein

Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein

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The H5N1 influenza virus in Indonesia has caused more than 100 people died due to the virus infections. Cases in humans were mostly due to the virus spread from the infected birds. This study characterized molecularly the H5N1 virus from birds around the H5N1 infection cases in humans in Indonesia....

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Main Authors: NI LUH PUTU INDI DHARMAYANTI, FERA IBRAHIM, DARMINTO, AMIN SOEBANDRIO
Format: Article
Language:English
Published: Bogor Agricultural University 2011-06-01
Series:Hayati Journal of Biosciences
Subjects:
molecular character
H5N1 virus
birds
surrounding
human H5N1 infection
Online Access:http://molecular character, H5N1 virus, birds, surrounding, human H5N1 infection
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spelling doaj-1b8bc875235f485ab4bb2deca2b64e082020-11-24T23:26:36ZengBogor Agricultural UniversityHayati Journal of Biosciences1978-30192086-40942011-06-011828290Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix ProteinNI LUH PUTU INDI DHARMAYANTIFERA IBRAHIMDARMINTOAMIN SOEBANDRIOThe H5N1 influenza virus in Indonesia has caused more than 100 people died due to the virus infections. Cases in humans were mostly due to the virus spread from the infected birds. This study characterized molecularly the H5N1 virus from birds around the H5N1 infection cases in humans in Indonesia. Result from this study revealed that in several cases, waterfowl species could become the source of H5N1 infections in human. We found that the one of six viruses used in this study probably was a first antigenic shift virus in Indonesia. This study shows that the AI viruses isolated from birds around humans infected by H5N1 virus has specific characteristics namely the presence of several amino acid substitutions especially on the M1 and M2 proteins. The substitutions are similar in most of H5N1 human cases in Indonesia.molecular character, H5N1 virus, birds, surrounding, human H5N1 infectionmolecular characterH5N1 virusbirdssurroundinghuman H5N1 infection
collection DOAJ
language English
format Article
sources DOAJ
author NI LUH PUTU INDI DHARMAYANTI
FERA IBRAHIM
DARMINTO
AMIN SOEBANDRIO
spellingShingle NI LUH PUTU INDI DHARMAYANTI
FERA IBRAHIM
DARMINTO
AMIN SOEBANDRIO
Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
Hayati Journal of Biosciences
molecular character
H5N1 virus
birds
surrounding
human H5N1 infection
author_facet NI LUH PUTU INDI DHARMAYANTI
FERA IBRAHIM
DARMINTO
AMIN SOEBANDRIO
author_sort NI LUH PUTU INDI DHARMAYANTI
title Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
title_short Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
title_full Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
title_fullStr Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
title_full_unstemmed Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein
title_sort influenza h5n1 virus of birds surrounding h5n1 human cases have specific characteristics on the matrix protein
publisher Bogor Agricultural University
series Hayati Journal of Biosciences
issn 1978-3019
2086-4094
publishDate 2011-06-01
description The H5N1 influenza virus in Indonesia has caused more than 100 people died due to the virus infections. Cases in humans were mostly due to the virus spread from the infected birds. This study characterized molecularly the H5N1 virus from birds around the H5N1 infection cases in humans in Indonesia. Result from this study revealed that in several cases, waterfowl species could become the source of H5N1 infections in human. We found that the one of six viruses used in this study probably was a first antigenic shift virus in Indonesia. This study shows that the AI viruses isolated from birds around humans infected by H5N1 virus has specific characteristics namely the presence of several amino acid substitutions especially on the M1 and M2 proteins. The substitutions are similar in most of H5N1 human cases in Indonesia.
topic molecular character
H5N1 virus
birds
surrounding
human H5N1 infection
url http://molecular character, H5N1 virus, birds, surrounding, human H5N1 infection
work_keys_str_mv AT niluhputuindidharmayanti influenzah5n1virusofbirdssurroundingh5n1humancaseshavespecificcharacteristicsonthematrixprotein
AT feraibrahim influenzah5n1virusofbirdssurroundingh5n1humancaseshavespecificcharacteristicsonthematrixprotein
AT darminto influenzah5n1virusofbirdssurroundingh5n1humancaseshavespecificcharacteristicsonthematrixprotein
AT aminsoebandrio influenzah5n1virusofbirdssurroundingh5n1humancaseshavespecificcharacteristicsonthematrixprotein
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