A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)

Bibliographic Details
Main Authors: SJ Allen, K Wareham, D Wang, C Bradley, B Sewell, H Hutchings, W Harris, A Dhar, H Brown, A Foden, MB Gravenor, D Mack, CJ Phillips
Format: Article
Language:English
Published: NIHR Journals Library 2013-12-01
Series:Health Technology Assessment
Online Access:https://doi.org/10.3310/hta17570
id doaj-1b87f16a3bdf4d8eab99a5d1bade0876
record_format Article
spelling doaj-1b87f16a3bdf4d8eab99a5d1bade08762020-11-25T01:17:21ZengNIHR Journals LibraryHealth Technology Assessment2046-49242013-12-01175710.3310/hta1757006/39/02A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)SJ Allen0K WarehamD WangC BradleyB SewellH HutchingsW HarrisA DharH BrownA FodenMB GravenorD MackCJ PhillipsCollege of Medicine, Swansea University, Swansea, UKhttps://doi.org/10.3310/hta17570
collection DOAJ
language English
format Article
sources DOAJ
author SJ Allen
K Wareham
D Wang
C Bradley
B Sewell
H Hutchings
W Harris
A Dhar
H Brown
A Foden
MB Gravenor
D Mack
CJ Phillips
spellingShingle SJ Allen
K Wareham
D Wang
C Bradley
B Sewell
H Hutchings
W Harris
A Dhar
H Brown
A Foden
MB Gravenor
D Mack
CJ Phillips
A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
Health Technology Assessment
author_facet SJ Allen
K Wareham
D Wang
C Bradley
B Sewell
H Hutchings
W Harris
A Dhar
H Brown
A Foden
MB Gravenor
D Mack
CJ Phillips
author_sort SJ Allen
title A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
title_short A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
title_full A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
title_fullStr A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
title_full_unstemmed A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
title_sort high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (placide)
publisher NIHR Journals Library
series Health Technology Assessment
issn 2046-4924
publishDate 2013-12-01
url https://doi.org/10.3310/hta17570
work_keys_str_mv AT sjallen ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT kwareham ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT dwang ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT cbradley ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT bsewell ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT hhutchings ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT wharris ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT adhar ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT hbrown ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT afoden ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT mbgravenor ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT dmack ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT cjphillips ahighdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT sjallen highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT kwareham highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT dwang highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT cbradley highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT bsewell highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT hhutchings highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT wharris highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT adhar highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT hbrown highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT afoden highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT mbgravenor highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT dmack highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
AT cjphillips highdosepreparationoflactobacilliandbifidobacteriainthepreventionofantibioticassociatedandclostridiumdifficilediarrhoeainolderpeopleadmittedtohospitalamulticentrerandomiseddoubleblindplacebocontrolledparallelarmtrialplacide
_version_ 1725146414813544448