Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins : Implication for microbicide development

Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins : Implication for microbicide development

<p>Abstract</p> <p>Background</p> <p>Plant lectins such as <it>Galanthus nivalis </it>agglutinin (GNA) and <it>Hippeastrum hybrid </it>agglutinin (HHA) are natural proteins able to link mannose residues, and therefore inhibit HIV-target cell inte...

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Bibliographic Details
Main Authors: Balzarini Jan, Krief Corinne, Schols Dominique, Lecerf Maxime, Nasreddine Nadine, Jenabian Mohammad-Ali, Saïdi Hela, Bélec Laurent
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/28

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