The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis.

The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a common, progressive and invariably lethal interstitial lung disease with no effective therapy. We hypothesised that K(Ca)3.1 K(+) channel-dependent cell processes contribute to IPF pathophysiology.K(Ca)3.1 expression in primary human lung myofibroblasts was e...

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Bibliographic Details
Main Authors: Katy M Roach, Stephen Mark Duffy, William Coward, Carol Feghali-Bostwick, Heike Wulff, Peter Bradding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877378?pdf=render

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