A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol

A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol

Abstract Background The COVID-19 pandemic reached Europe in early 2020. Convalescent plasma is used without a consistent evidence of efficacy. Our hypothesis is that passive immunization with plasma collected from patients having contracted COVID-19 and developed specific neutralizing antibodies may...

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Bibliographic Details
Main Authors: Benoît Misset, Eric Hoste, Anne-Françoise Donneau, David Grimaldi, Geert Meyfroidt, Michel Moutschen, Veerle Compernolle, André Gothot, Daniel Desmecht, Mutien Garigliany, Tome Najdovski, Pierre-François Laterre
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Pulmonary Medicine
Subjects:
COVID-19
Convalescent plasma
Randomized
Respiratory failure
Mechanical ventilation
Online Access:https://doi.org/10.1186/s12890-020-01361-x

Internet

https://doi.org/10.1186/s12890-020-01361-x

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