Peripheral PD-1+CD56+ T-cell frequencies correlate with outcome in stage IV melanoma under PD-1 blockade.

Peripheral PD-1+CD56+ T-cell frequencies correlate with outcome in stage IV melanoma under PD-1 blockade.

Immune checkpoint blockade with anti-PD-1 antibodies is showing great promise for patients with metastatic melanoma and other malignancies, but despite good responses by some patients who achieve partial or complete regression, many others still do not respond. Here, we sought peripheral blood T-cel...

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Bibliographic Details
Main Authors: Jonas Bochem, Henning Zelba, Teresa Amaral, Janine Spreuer, Daniel Soffel, Thomas Eigentler, Nikolaus Benjamin Wagner, Ugur Uslu, Patrick Terheyden, Friedegund Meier, Claus Garbe, Graham Pawelec, Benjamin Weide, Kilian Wistuba-Hamprecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221301

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