APC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencing.

APC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencing.

<h4>Background</h4>Selective protein degradation via the ubiquitin-26S proteasome is a major mechanism underlying DNA replication and cell division in all Eukaryotes. In particular, the APC/C (Anaphase Promoting Complex or Cyclosome) is a master ubiquitin protein ligase (E3) that targets...

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Bibliographic Details
Main Authors: Katia Marrocco, Marie-Claire Criqui, Jérôme Zervudacki, Gregory Schott, Herfried Eisler, Aude Parnet, Patrice Dunoyer, Pascal Genschik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22545099/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22545099/pdf/?tool=EBI

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