The inflammasome pathway in stable COPD and acute exacerbations

The inflammasome pathway in stable COPD and acute exacerbations

Chronic obstructive pulmonary disease (COPD) is characterised by pulmonary and systemic inflammation that bursts during exacerbations of the disease (ECOPD). The NLRP3 inflammasome is a key regulatory molecule of the inflammatory response. Its role in COPD is unclear. We investigated the NLRP3 infla...

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Main Authors: Rosa Faner, Patricia Sobradillo, Aina Noguera, Cristina Gomez, Tamara Cruz, Alejandra López-Giraldo, Eugeni Ballester, Nestor Soler, Juan I. Arostegui, Pablo Pelegrín, Roberto Rodriguez-Roisin, Jordi Yagüe, Borja G. Cosio, Manel Juan, Alvar Agustí
Format: Article
Language:English
Published: European Respiratory Society 2016-07-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/2/3/00002-2016.full

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