Anti-inflammatory and Anti-ulcer Activities of New Fused Thiazole Derivatives Derived from 2-(2-Oxo-2H-chromen-3-yl)thiazol-4(5H)-one

Anti-inflammatory and Anti-ulcer Activities of New Fused Thiazole Derivatives Derived from 2-(2-Oxo-2H-chromen-3-yl)thiazol-4(5H)-one

The reaction of the 2-(4-oxo-4,5-dihydrothiazol-2-yl)acetonitrile (1) with salicylaldehyde (2) in 1,4-dioxane containing a catalytic amount of piperidine gave the coumarin derivative 3. The latter reacted with different reagents to give pyrano[4,5-b]thiazole, pyrido[4,5-b]thiazole and thieno[5,4-b]t...

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Bibliographic Details
Main Authors: Rafat Mohareb, Fatima Al-Omran, Mahmoud Abdelaziz, Rehab Ibrahim
Format: Article
Language:English
Published: Slovenian Chemical Society 2017-06-01
Series:Acta Chimica Slovenica
Subjects:
4,5-dihydrothiazol
coumarin
pyrimidine
anti inflammatory
antiulcer activity
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/3200

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