Automated high-throughput quantification of mitotic spindle positioning from DIC movies of Caenorhabditis embryos.

Automated high-throughput quantification of mitotic spindle positioning from DIC movies of Caenorhabditis embryos.

The mitotic spindle is a microtubule-based structure that elongates to accurately segregate chromosomes during anaphase. Its position within the cell also dictates the future cell cleavage plan, thereby determining daughter cell orientation within a tissue or cell fate adoption for polarized cells....

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Bibliographic Details
Main Authors: David Cluet, Pierre-Nicolas Stébé, Soizic Riche, Martin Spichty, Marie Delattre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3998942?pdf=render

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