NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein

NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein

Membrane targeting by the Gag proteins of the human immunodeficiency viruses (HIV types-1 and -2) is mediated by Gag’s N-terminally myristylated matrix (MA) domain and is dependent on cellular phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2]. To determine if other lentiviruses employ a similar memb...

Full description

Bibliographic Details
Main Authors: Lola A. Brown, Cassiah Cox, Janae Baptiste, Holly Summers, Ryan Button, Kennedy Bahlow, Vaughn Spurrier, Jenna Kyser, Benjamin G. Luttge, Lillian Kuo, Eric O. Freed, Michael F. Summers
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Viruses
Subjects:
Feline immunodeficiency virus (FIV)
nuclear magnetic resonance (NMR)
protein structure
retrovirus assembly
membrane targeting
phosphatidylinositol-4,5-bisphosphate [PI(4,5)-P2
PIP2]
Online Access:http://www.mdpi.com/1999-4915/7/5/2210

Internet

http://www.mdpi.com/1999-4915/7/5/2210

Similar Items