Key Amino Acids in the Bacterial (6-4) Photolyase PhrB from Agrobacterium fabrum.

Photolyases can repair pyrimidine dimers on the DNA that are formed during UV irradiation. PhrB from Agrobacterium fabrum represents a new group of prokaryotic (6-4) photolyases which contain an iron-sulfur cluster and a DMRL chromophore. We performed site-directed mutagenesis in order to assess the...

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Bibliographic Details
Main Authors: Dominik Graf, Janine Wesslowski, Hongju Ma, Patrick Scheerer, Norbert Krauß, Inga Oberpichler, Fan Zhang, Tilman Lamparter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619345?pdf=render