MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus

MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus

Abstract Long-term memory formation is supported by functional and structural changes of neuronal networks, which rely on de novo gene transcription and protein synthesis. The modulation of the neuronal transcriptome in response to learning depends on transcriptional and post-transcriptional mechani...

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Bibliographic Details
Main Authors: David V. C. Brito, Kubra Gulmez Karaca, Janina Kupke, Lukas Frank, Ana M. M. Oliveira
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Brain
Subjects:
Alternative splicing
Adult brain
DNA methylation
Gene transcription
Rett syndrome
RNA sequencing
Online Access:http://link.springer.com/article/10.1186/s13041-020-00695-1

Internet

http://link.springer.com/article/10.1186/s13041-020-00695-1

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