Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil
<abstract language="eng">The chaoolmugra oil is one of the oldest medicines used for leprosy until the development of sulfas. In Brazil, it is known as sapucainha oil that is obtained from Carpotroche brasilienesis seeds (Flacourtiaceae). Chemical and medicinal studies of sapucainha...
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Sociedade Brasileira de Química
2009-01-01
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doaj-1b205dd4b5af4304917ebc02a05b68902020-11-25T01:11:37ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642009-01-0132113914510.1590/S0100-40422009000100027Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in BrazilAdriana S. OliveiraJosélia A. LimaClaudia M. RezendeAngelo C. Pinto<abstract language="eng">The chaoolmugra oil is one of the oldest medicines used for leprosy until the development of sulfas. In Brazil, it is known as sapucainha oil that is obtained from Carpotroche brasilienesis seeds (Flacourtiaceae). Chemical and medicinal studies of sapucainha oil were introduced in Brazil by Peckolt, Cole and Cardoso which showed that major ciclopentenyl fatty acids as chaulmoogric, hydnocarpic and gorlic were responsible for its bactericidal activity. In this work, a method for quantification of sapucainha oil acidic fraction by HRGC was established using methyl n-heptadecanoate as internal standard. The oil chemical stability was investigated by the use of GC-MS, IR, ¹H and 13C NMR and showed that the main degradation products belong to the cyclopentenyl moiety oxidation.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000100027Carpotroche brasiliensiscyclopentenyl fatty acidsantileprotic |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Adriana S. Oliveira Josélia A. Lima Claudia M. Rezende Angelo C. Pinto |
spellingShingle |
Adriana S. Oliveira Josélia A. Lima Claudia M. Rezende Angelo C. Pinto Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil Química Nova Carpotroche brasiliensis cyclopentenyl fatty acids antileprotic |
author_facet |
Adriana S. Oliveira Josélia A. Lima Claudia M. Rezende Angelo C. Pinto |
author_sort |
Adriana S. Oliveira |
title |
Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil |
title_short |
Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil |
title_full |
Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil |
title_fullStr |
Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil |
title_full_unstemmed |
Ácidos ciclopentênicos do óleo da sapucainha (Carpotroche brasiliensis Endl, Flacourtiaceae): o primeiro antileprótico usado no Brasil Cyclopentenyl acids from sapucainha oil (Carpotroche brasiliensis Endl, Flacourtiaceae): the first antileprotic used in Brazil |
title_sort |
ácidos ciclopentênicos do óleo da sapucainha (carpotroche brasiliensis endl, flacourtiaceae): o primeiro antileprótico usado no brasil cyclopentenyl acids from sapucainha oil (carpotroche brasiliensis endl, flacourtiaceae): the first antileprotic used in brazil |
publisher |
Sociedade Brasileira de Química |
series |
Química Nova |
issn |
0100-4042 1678-7064 |
publishDate |
2009-01-01 |
description |
<abstract language="eng">The chaoolmugra oil is one of the oldest medicines used for leprosy until the development of sulfas. In Brazil, it is known as sapucainha oil that is obtained from Carpotroche brasilienesis seeds (Flacourtiaceae). Chemical and medicinal studies of sapucainha oil were introduced in Brazil by Peckolt, Cole and Cardoso which showed that major ciclopentenyl fatty acids as chaulmoogric, hydnocarpic and gorlic were responsible for its bactericidal activity. In this work, a method for quantification of sapucainha oil acidic fraction by HRGC was established using methyl n-heptadecanoate as internal standard. The oil chemical stability was investigated by the use of GC-MS, IR, ¹H and 13C NMR and showed that the main degradation products belong to the cyclopentenyl moiety oxidation. |
topic |
Carpotroche brasiliensis cyclopentenyl fatty acids antileprotic |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000100027 |
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