DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans

DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans

Aging is accompanied by a progressive decline in immune function termed “immunosenescence”. Deficient surveillance coupled with the impaired function of immune cells compromises host defense in older animals. The dynamic activity of regulatory modules that control immunity appears to underlie age-de...

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Bibliographic Details
Main Authors: Daniel R. McHugh, Elena Koumis, Paul Jacob, Jennifer Goldfarb, Michelle Schlaubitz-Garcia, Safae Bennani, Paul Regan, Prem Patel, Matthew J. Youngman
Format: Article
Language:English
Published: Oxford University Press 2020-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
c. elegans
innate immunity
aging
daf-16
smk-1
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401166

Internet

http://g3journal.org/lookup/doi/10.1534/g3.120.401166

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