Abstract P-13: Structural Studies of Insulin Receptor-Related Receptor Ectodomain
Background: The insulin receptor-related receptor (IRR) was originally discovered due to its high homology to the other family members (insulin receptor and insulin-like growth factor 1 receptor). We determined that IRR can be activated by mildly alkaline extracellular media and has typical features...
Main Authors: | Andrey Mozhaev, Evgeny Pichkur, Igor Deyev, Ekaterina Mileshina, Anton Orekhov, Alexander Vasiliev, Alexander Petrenko |
---|---|
Format: | Article |
Language: | English |
Published: |
International Medical Research and Development Corporation
2021-06-01
|
Series: | International Journal of Biomedicine |
Subjects: | |
Online Access: | http://ijbm.org/articles/v11s1/ijbm_2021_11_s1_p13.pdf |
Similar Items
-
Site-Directed Mutagenesis of the Fibronectin Domains in Insulin Receptor-Related Receptor
by: Igor E. Deyev, et al.
Published: (2017-11-01) -
Flexibility in the Insulin Receptor Ectodomain Enables Docking of Insulin in Crystallographic Conformation Observed in a Hormone-Bound Microreceptor
by: Harish Vashisth
Published: (2014-10-01) -
Tyrosine Kinase Receptors in Oncology
by: Jorge Esteban-Villarrubia, et al.
Published: (2020-11-01) -
Autophosphorylation of Orphan Receptor ERBB2 Can Be Induced by Extracellular Treatment with Mildly Alkaline Media
by: Oxana V. Serova, et al.
Published: (2019-03-01) -
Landmarks in insulin research
by: Michael eLawrence, et al.
Published: (2011-11-01)