HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

<p>Abstract</p> <p>Background</p> <p>Infection with human immunodeficiency virus type-1 (HIV)-1 leads to some form of HIV-1-associated neurocognitive disorders (HAND) in approximately half of the cases. The mechanisms by which astrocytes contribute to HIV-1-associated d...

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Bibliographic Details
Main Authors: Mamik Manmeet K, Banerjee Sugato, Walseth Timothy F, Hirte Renee, Tang Lin, Borgmann Kathleen, Ghorpade Anuja
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/145

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