A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells

Living cells encounter many stimuli from the immediate environment. Receptors recognize these environmental cues and transduce signals to produce cell responses. The frequency of a signal is now emerging as an important factor determining cell responses. As a componentry system in understanding temp...

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Main Authors:	Zubaidah Ningsih, James W.M. Chon, Andrew H.A. Clayton
Format:	Article
Language:	English
Published:	AIMS Press 2015-03-01
Series:	AIMS Biophysics
Subjects:	microfluidic mixing lifetime spatiotemporal FLIM
Online Access:	http://www.aimspress.com/biophysics/article/280/fulltext.html

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spelling	doaj-1b05d26c8133419fa2ca8fefa65bac7c2020-11-25T00:19:02ZengAIMS PressAIMS Biophysics2377-90982015-03-0122587210.3934/biophy.2015.2.5820150258A Microfluidic Device for Spatiotemporal Delivery of Stimuli to CellsZubaidah Ningsih0James W.M. Chon1Andrew H.A. Clayton2Centre for Microphotonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, John Street PO BOX 218 Hawthorn VIC 3122 AustraliaCentre for Microphotonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, John Street PO BOX 218 Hawthorn VIC 3122 AustraliaCentre for Microphotonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology, John Street PO BOX 218 Hawthorn VIC 3122 AustraliaLiving cells encounter many stimuli from the immediate environment. Receptors recognize these environmental cues and transduce signals to produce cell responses. The frequency of a signal is now emerging as an important factor determining cell responses. As a componentry system in understanding temporal stimulation, microfluidic devices allow the observation of cell behaviour under dynamic stimulation and controllable environment. In this paper we describe the design, construction and characterization of a microfluidic device suitable for cell stimulation studies.http://www.aimspress.com/biophysics/article/280/fulltext.htmlmicrofluidicmixinglifetimespatiotemporalFLIM
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Zubaidah Ningsih James W.M. Chon Andrew H.A. Clayton
spellingShingle	Zubaidah Ningsih James W.M. Chon Andrew H.A. Clayton A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells AIMS Biophysics microfluidic mixing lifetime spatiotemporal FLIM
author_facet	Zubaidah Ningsih James W.M. Chon Andrew H.A. Clayton
author_sort	Zubaidah Ningsih
title	A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells
title_short	A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells
title_full	A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells
title_fullStr	A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells
title_full_unstemmed	A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells
title_sort	microfluidic device for spatiotemporal delivery of stimuli to cells
publisher	AIMS Press
series	AIMS Biophysics
issn	2377-9098
publishDate	2015-03-01
description	Living cells encounter many stimuli from the immediate environment. Receptors recognize these environmental cues and transduce signals to produce cell responses. The frequency of a signal is now emerging as an important factor determining cell responses. As a componentry system in understanding temporal stimulation, microfluidic devices allow the observation of cell behaviour under dynamic stimulation and controllable environment. In this paper we describe the design, construction and characterization of a microfluidic device suitable for cell stimulation studies.
topic	microfluidic mixing lifetime spatiotemporal FLIM
url	http://www.aimspress.com/biophysics/article/280/fulltext.html
work_keys_str_mv	AT zubaidahningsih amicrofluidicdeviceforspatiotemporaldeliveryofstimulitocells AT jameswmchon amicrofluidicdeviceforspatiotemporaldeliveryofstimulitocells AT andrewhaclayton amicrofluidicdeviceforspatiotemporaldeliveryofstimulitocells AT zubaidahningsih microfluidicdeviceforspatiotemporaldeliveryofstimulitocells AT jameswmchon microfluidicdeviceforspatiotemporaldeliveryofstimulitocells AT andrewhaclayton microfluidicdeviceforspatiotemporaldeliveryofstimulitocells
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A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells

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