Data on atherosclerosis specific antibody conjugation to nanoemulsions

Data on atherosclerosis specific antibody conjugation to nanoemulsions

This article present data related to the publication entitled âIron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imagingâ (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scF...

Full description

Bibliographic Details
Main Authors: Geoffrey Prévot, Martine Duonor-Cérutti, Mélusine Larivière, Jeanny Laroche-Traineau, Marie Josée Jacobin-Valat, Philippe Barthélémy, Gisèle Clofent-Sanchez, Sylvie Crauste-Manciet
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340917305796
Description
Summary:This article present data related to the publication entitled âIron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imagingâ (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits.
ISSN:2352-3409

Similar Items