Diagnostic RAS mutation analysis by polymerase chain reaction (PCR)

RAS mutation analysis is an important companion diagnostic test. Treatment of colorectal cancer with anti-Epidermal Growth Factor Receptor (EGFR) therapy requires demonstration of RAS mutation status (both KRAS and NRAS), and it is good practice to include BRAF. In Non-Small Cell Lung Cancer (NSCLC)...

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Bibliographic Details
Main Author: Ian A. Cree
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Biomolecular Detection and Quantification
Subjects:
PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2214753516300080