Association of RYR2 Mutation With Tumor Mutation Burden, Prognosis, and Antitumor Immunity in Patients With Esophageal Adenocarcinoma

Association of RYR2 Mutation With Tumor Mutation Burden, Prognosis, and Antitumor Immunity in Patients With Esophageal Adenocarcinoma

Background: Esophageal adenocarcinoma (EAC) remains a leading cause of cancer-related deaths worldwide and demonstrates a predominant rising incidence in Western countries. Recently, immunotherapy has dramatically changed the landscape of treatment for many advanced cancers, with the benefit in EAC...

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Bibliographic Details
Main Authors: Zaoqu Liu, Long Liu, Dechao Jiao, Chunguang Guo, Libo Wang, Zhaonan Li, Zhenqiang Sun, Yanan Zhao, Xinwei Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
esophageal adenocarcinoma
mutation
RYR2
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.669694/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.669694/full

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