Lymph Nodes and Cancer Metastasis: New Perspectives on the Role of Intranodal Lymphatic Sinuses

Lymph Nodes and Cancer Metastasis: New Perspectives on the Role of Intranodal Lymphatic Sinuses

The lymphatic system is essential for transporting interstitial fluid, soluble antigen, and immune cells from peripheral tissues to lymph nodes (LNs). Functional integrity of LNs is dependent on intact lymphatics and effective lymph drainage. Molecular mechanisms that facilitate interactions between...

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Bibliographic Details
Main Author: Rui-Cheng Ji
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
lymph nodes
lymphatic endothelial cells
cancer metastasis
lymphangiogenesis
VEGF-A/-C/-D
Online Access:http://www.mdpi.com/1422-0067/18/1/51

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