A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis
Camptothecin is a monoterpene indole alkaloid with anti-tumor activity. Here, the authors assemble the genome of the camptothecin producing plant Camptotheca acuminata and provide insights into the evolutionary origin of camptothecin biosynthesis by comparing to the vinblastine and vincristine biosy...
Main Authors: | Minghui Kang, Rao Fu, Pingyu Zhang, Shangling Lou, Xuchen Yang, Yang Chen, Tao Ma, Yang Zhang, Zhenxiang Xi, Jianquan Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-23872-9 |
Similar Items
-
Pyrosequencing of the <it>Camptotheca acuminata </it>transcriptome reveals putative genes involved in camptothecin biosynthesis and transport
by: Sun Yongzhen, et al.
Published: (2011-10-01) -
Effects of camptothecin content of Camptotheca acuminata by field management technique
by: Shih-Jhe Shen, et al.
Published: (2008) -
Cellular localisation of the anti-cancer drug camptothecin in Camptotheca acuminata Decne (Nyssaceae)
by: G Pasqua, et al.
Published: (2009-06-01) -
Propagation of Camptotheca acuminata
by: Maxwell, Douglas Wayne
Published: (2004) -
Cell-specific expression of tryptophan decarboxylase and 10-hydroxygeraniol oxidoreductase, key genes involved in camptothecin biosynthesis in <it>Camptotheca acuminata </it>Decne (Nyssaceae)
by: Santamaria Anna, et al.
Published: (2010-04-01)