Forced notch signaling inhibits commissural axon outgrowth in the developing chick central nerve system.

BACKGROUND: A collection of in vitro evidence has demonstrated that Notch signaling plays a key role in the growth of neurites in differentiated neurons. However, the effects of Notch signaling on axon outgrowth in an in vivo condition remain largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: In this...

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Bibliographic Details
Main Authors: Ming Shi, Zhirong Liu, Yonggang Lv, Minhua Zheng, Fang Du, Gang Zhao, Ying Huang, Jiayin Chen, Hua Han, Yuqiang Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024975?pdf=render