Analysis Mortality in Patients with HIV-infection on Example of a Region with a High Prevalence of Infection

• Main Authors: V. Ya. Rosenberg, Yu. K. Plotnikova, E. E. Voronin
• Format: Article
• Language: Russian
• Published: Numikom LLC 2018-02-01
• Series: Эпидемиология и вакцинопрофилактика
• Subjects: hiv infection; aids; mortality; tuberculosis; pneumonia the key role of the pathology of the respiratory system (tuberculosis; pneumonia) in the structure of mortality is shown; as well as the clear positive effect of antiretroviral therapy on the development of aids and the survival of patients with hiv infection
• Online Access: https://www.epidemvac.ru/jour/article/view/399
• ISSN: 2073-3046; 2619-0494

Relevance The HIV epidemic, registered worldwide since the early 1980s, is currently continuing its development in most countries, and, according to the Joint United Nations Program on HIV/AIDS (UNAIDS, 2016), covers more than 36 million people (including 1.8 million children) AIDS mortality is a key indicator of the effectiveness of the response to the HIV epidemic. On the example of the Irkutsk region as a region with high lesion, an analysis of the main indicators and causes of death of patients with HIV infection was carried out.Goal – analysis of the mortality of HIV / AIDS patients by the example of a region with a high degree of defeat in order to determine the key criteria for evaluating activities to reduce the mortality from HIV/AIDS.Materials and methods An analysis was made of the causes of mortality of patients with HIV infection in the Irkutsk region in 2014– 2016, using comparative data of modern domestic and foreign literature (including total mortality), as well as accounting and reporting documentation of the Irkutsk Regional Center for prevention and control of AIDS and infectious diseases.Results 1. There is an increase in the death rate of HIV-infected people, including those caused by HIV. 2. The increase in mortality practically does not lead to an increase in mortality due to a parallel increase in the number of people living with HIV. 3. The main causes of death from HIV infection (AIDS) are pathologies with primary respiratory system damage: tuberculosis and pneumonia, which requires special attention in developing approaches to diagnosis, recording, treatment and prevention of these diseases, as well as assessing the impact of vaccination of patients with HIV infection against pneumococcus on mortality from pneumonia. 4. The increase in ART coverage of all patient populations contributes to the stabilization of mortality from HIV/AIDS.Conclusions: the most important for assessing the impact of ongoing efforts of the health system to reduce mortality among HIVinfected patients is the correct registration and diagnosis (including posthumous) of AIDS-indicative diseases, certainly associated with the progression of HIV infection.