Location, Location, Location: The Role of Nuclear Positioning in the Repair of Collapsed Forks and Protection of Genome Stability

Components of the nuclear pore complex (NPC) have been shown to play a crucial role in protecting against replication stress, and recovery from some types of stalled or collapsed replication forks requires movement of the DNA to the NPC in order to maintain genome stability. The role that nuclear po...

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Bibliographic Details
Main Authors: Jenna M. Whalen, Catherine H. Freudenreich
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/6/635