Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]

A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination. A fifth central tumor corresponded to a conventional clear cell renal cell carcinoma. Biphasic squamoid alveolar renal cell car...

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Main Author: Jose Ignacio Lopez
Format: Article
Language:English
Published: F1000 Research Ltd 2016-04-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-607/v1
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spelling doaj-1acaa49852664010b2472feafc2926b22020-11-25T03:32:08ZengF1000 Research LtdF1000Research2046-14022016-04-01510.12688/f1000research.8451.19099Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]Jose Ignacio Lopez0Department of Pathology, Cruces University Hospital, Biocruces Health Research Institute, University of the Basque Country (UPV/EHU), Barakaldo, SpainA multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination. A fifth central tumor corresponded to a conventional clear cell renal cell carcinoma. Biphasic squamoid alveolar renal cell carcinoma is a rare tumor that has been very recently characterized as a distinct histotype within the spectrum of papillary renal cell carcinoma. Immunostaining with cyclin D1 seems to be specific of this tumor subtype. This is the first reported case with multifocal presentation.http://f1000research.com/articles/5-607/v1Cancer in the ElderlyGastrointestinal Cancers
collection DOAJ
language English
format Article
sources DOAJ
author Jose Ignacio Lopez
spellingShingle Jose Ignacio Lopez
Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
F1000Research
Cancer in the Elderly
Gastrointestinal Cancers
author_facet Jose Ignacio Lopez
author_sort Jose Ignacio Lopez
title Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
title_short Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
title_full Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
title_fullStr Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
title_full_unstemmed Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
title_sort case report: multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2016-04-01
description A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination. A fifth central tumor corresponded to a conventional clear cell renal cell carcinoma. Biphasic squamoid alveolar renal cell carcinoma is a rare tumor that has been very recently characterized as a distinct histotype within the spectrum of papillary renal cell carcinoma. Immunostaining with cyclin D1 seems to be specific of this tumor subtype. This is the first reported case with multifocal presentation.
topic Cancer in the Elderly
Gastrointestinal Cancers
url http://f1000research.com/articles/5-607/v1
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