Modulation of all-trans retinoic acid-induced MiRNA expression in neoplastic cell lines: a systematic review

Abstract Background Cancer is a genetic and epigenetic disease that involves inactivation of tumor suppressor genes and activation of proto-oncogenes. All-trans retinoic acid (ATRA) is an isomer of retinoic acid involved in the onset of differentiation and apoptosis of a number of normal and cancer...

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Main Authors: Lara Lima, Thaísa Cristina Tavares de Melo, Diego Marques, Jéssica Nayara Góes de Araújo, Isabela Samária Fernandes Leite, Camila Xavier Alves, Julieta Genre, Vivian Nogueira Silbiger
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-019-6081-7