Dwarfism and insulin resistance in male offspring caused by α1-adrenergic antagonism during pregnancy

Dwarfism and insulin resistance in male offspring caused by α1-adrenergic antagonism during pregnancy

Objective: Maternal and environmental factors control the epigenetic fetal programming of the embryo, thereby defining the susceptibility for metabolic or endocrine disorders in the offspring. Pharmacological interventions required as a consequence of gestational problems, e.g. hypertension, can pot...

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Bibliographic Details
Main Authors: Rebecca Oelkrug, Beate Herrmann, Cathleen Geissler, Lisbeth Harder, Christiane Koch, Hendrik Lehnert, Henrik Oster, Henriette Kirchner, Jens Mittag
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Molecular Metabolism
Subjects:
Brown fat
Pregnancy
Thermogenesis
Fever
Insulin resistance
IGF-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817303678

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