Leiomyosarcoma of the Inferior Venacava: A Case Report

• Main Authors: Diksha Karki, Paricha Upadhayaya, Purbesh Adhikari, Mona Dahal, Bishow Prakash Jung Thapa, Bandana Mudbhari, Gopal Lama, Neera Pathak
• Format: Article
• Language: English
• Published: Nepal Medical Association 2019-06-01
• Series: Journal of Nepal Medical Association
• Subjects: actins; vena cava; leiomyosarcoma; smooth muscle.
• Online Access: https://www.jnma.com.np/jnma/index.php/jnma/article/view/4455

Leiomyosarcoma of inferior venacava is a rare tumor. Female are most commonly affected and middle segment of inferior vena cava is the commonest site. The diagnosis can sometimes be challenging as patients present with non-specific symptoms. We present a case of a 65-year-old female who presented with pain in hypochondrium and epigastric region since 4 months along with weight loss, anorexia and vomiting. Histopathological examination revealed a capsulated, multilobated tumor arising from muscle layer of inferior venacava with extraluminal growth pattern and tumor cells showing cytoplasmic positivity for immuno-histochemical stain smooth muscle actin. With the diagnosis of leiomyosarcoma of inferior venacava, excision of tumor was done with tangential excision of 4 cm length of inferior venacava with primary repair.