A comprehensive search for recombinogenic motifs in the human genome.

A comprehensive search for recombinogenic motifs in the human genome.

The patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of a...

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Main Authors: Henry R Johnston, David J Cutler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633838?pdf=render
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spelling doaj-1a992a42403f4356ba2c6faac459983f2020-11-25T01:55:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0184e6292010.1371/journal.pone.0062920A comprehensive search for recombinogenic motifs in the human genome.Henry R JohnstonDavid J CutlerThe patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of all small motifs in an attempt to identify one or more that match to the available data. In the end, we conclude that no such motifs appear to exist in the human genome.http://europepmc.org/articles/PMC3633838?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Henry R Johnston
David J Cutler
spellingShingle Henry R Johnston
David J Cutler
A comprehensive search for recombinogenic motifs in the human genome.
PLoS ONE
author_facet Henry R Johnston
David J Cutler
author_sort Henry R Johnston
title A comprehensive search for recombinogenic motifs in the human genome.
title_short A comprehensive search for recombinogenic motifs in the human genome.
title_full A comprehensive search for recombinogenic motifs in the human genome.
title_fullStr A comprehensive search for recombinogenic motifs in the human genome.
title_full_unstemmed A comprehensive search for recombinogenic motifs in the human genome.
title_sort comprehensive search for recombinogenic motifs in the human genome.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2013-01-01
description The patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of all small motifs in an attempt to identify one or more that match to the available data. In the end, we conclude that no such motifs appear to exist in the human genome.
url http://europepmc.org/articles/PMC3633838?pdf=render
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AT henryrjohnston comprehensivesearchforrecombinogenicmotifsinthehumangenome
AT davidjcutler comprehensivesearchforrecombinogenicmotifsinthehumangenome
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