Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives

Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives

A series of novel 2-phenyl-4-trifluoromethyl thiazole-5-carboxamide derivatives have been synthesized and evaluated for their anticancer activity against A-549, Bel7402, and HCT-8 cell lines. Among the tested compounds, highest activity (48%) was achieved with the 4-chloro-2-methylphenyl amido subst...

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Bibliographic Details
Main Authors:	Wen-Xi Cai, Ai-Lin Liu, Zheng-Ming Li, Wei-Li Dong, Xing-Hai Liu, Na-Bo Sun
Format:	Article
Language:	English
Published:	MDPI AG 2016-01-01
Series:	Applied Sciences
Subjects:	thiazole amide synthesis antitumour
Online Access:	http://www.mdpi.com/2076-3417/6/1/8

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