Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic leukemia

Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic leukemia

Abstract Background Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gained lot of attention as a regulatory epigenetic modi...

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Bibliographic Details
Main Authors: Sara Wernig-Zorc, Mukesh Pratap Yadav, Pradeep Kumar Kopparapu, Mats Bemark, Hallgerdur Lind Kristjansdottir, Per-Ola Andersson, Chandrasekhar Kanduri, Meena Kanduri
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Epigenetics & Chromatin
Subjects:
Hydroxymethylation
CpG islands
Enhancers and chronic lymphocytic leukemia
Online Access:http://link.springer.com/article/10.1186/s13072-018-0252-7

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