Osteopontin level in synovial fluid is associated with the severity of joint pain and cartilage degradation after anterior cruciate ligament rupture.

To explore the molecular function of Osteopontin (OPN) in the pathogenesis of human OA, we compared the expression levels of OPN in synovial fluid with clinical parameters such as arthroscopic observation of cartilage damage and joint pain after joint injury.Synovial fluid was obtained from patients...

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Bibliographic Details
Main Authors: Mika Yamaga, Kunikazu Tsuji, Kazumasa Miyatake, Jun Yamada, Kahaer Abula, Young-Jin Ju, Ichiro Sekiya, Takeshi Muneta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3499533?pdf=render