Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis

Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis

<p>Abstract</p> <p>Background</p> <p>The inbred mouse strain BTBR T+ tf/J (BTBR) exhibits behavioral deficits that mimic the core deficits of autism. Neuroanatomically, the BTBR strain is also characterized by a complete absence of the corpus callosum. The goal of this...

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Main Authors: Stephenson Diane T, O'Neill Sharon M, Narayan Sapna, Tiwari Aadhya, Arnold Elizabeth, Samaroo Harry D, Du Fu, Ring Robert H, Campbell Brian, Pletcher Mathew, Vaidya Vidita A, Morton Daniel
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Molecular Autism
Online Access:http://www.molecularautism.com/content/2/1/7

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