Direct Analysis of hCGβcf Glycosylation in Normal and Aberrant Pregnancy by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Direct Analysis of hCGβcf Glycosylation in Normal and Aberrant Pregnancy by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

The analysis of human chorionic gonadotropin (hCG) in clinical chemistry laboratories by specific immunoassay is well established. However, changes in glycosylation are not as easily assayed and yet alterations in hCG glycosylation is associated with abnormal pregnancy. hCGβ-core fragment (hCGβcf) w...

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Bibliographic Details
Main Authors: Ray K. Iles, Laurence A. Cole, Stephen A. Butler
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:International Journal of Molecular Sciences
Subjects:
hCG
hCGβcf
MALDI TOF MS
pregnancy
hydatidiform mole
hyperemesis gravidarum
glycosylation
Online Access:http://www.mdpi.com/1422-0067/15/6/10067

Internet

http://www.mdpi.com/1422-0067/15/6/10067

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