Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells.

BACKGROUND:Directed differentiation of human induced pluripotent stem cells (hiPSC) into functional, region-specific neural cells is a key step to realizing their therapeutic promise to treat various neural disorders, which awaits detailed elucidation. METHODOLOGY/PRINCIPAL FINDINGS:We analyzed neur...

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Bibliographic Details
Main Authors: Hui Zeng, Min Guo, Kristen Martins-Taylor, Xiaofang Wang, Zheng Zhang, Jung Woo Park, Shuning Zhan, Mark S Kronenberg, Alexander Lichtler, Hui-Xia Liu, Fang-Ping Chen, Lixia Yue, Xue-Jun Li, Ren-He Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912324?pdf=render