Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread

Central nervous system involvement in multiple myeloma (CNS-MM) is a rare condition. Various manifestations of CNS-MM have been reported, including dural, parenchymal, and leptomeningeal involvement. Among them, leptomeningeal involvement is less common and intraventricular involvement is exceptiona...

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Main Authors: Jung Eun Lee, Eun Ja Lee, Hee Jin Huh, Jae-Woo Chung, Eun Kyoung Lee, Hyun Jung Lee
Format: Article
Language:English
Published: The Korean Society of Radiology 2018-07-01
Series:대한영상의학회지
Subjects:
Online Access:https://doi.org/10.3348/jksr.2018.79.1.50
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spelling doaj-1a3fd16a49fe4f23ae5adb6d5cff96d72020-11-25T01:44:35ZengThe Korean Society of Radiology대한영상의학회지1738-26372288-29282018-07-017915055https://doi.org/10.3348/jksr.2018.79.1.50Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal SpreadJung Eun Lee0Eun Ja Lee1Hee Jin Huh2Jae-Woo Chung3Eun Kyoung Lee4Hyun Jung Lee5Department of Radiology, Dongguk University Ilsan Hospital, Goyang, KoreaDepartment of Radiology, Dongguk University Ilsan Hospital, Goyang, KoreaDepartment of Laboratory Medicine, Dongguk University Ilsan Hospital, Goyang, KoreaDepartment of Laboratory Medicine, Dongguk University Ilsan Hospital, Goyang, KoreaDepartment of Radiology, Dongguk University Ilsan Hospital, Goyang, KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, KoreaCentral nervous system involvement in multiple myeloma (CNS-MM) is a rare condition. Various manifestations of CNS-MM have been reported, including dural, parenchymal, and leptomeningeal involvement. Among them, leptomeningeal involvement is less common and intraventricular involvement is exceptional, with only one case reported in the literature. Herein, we report the first case of CNS-MM manifesting as an intraventricular mass with leptomeningeal involvement combined with perineural spread. We also describe characteristic computed tomography and magnetic resonance imaging findings of intraventricular multiple myeloma.https://doi.org/10.3348/jksr.2018.79.1.50multiple myelomacentral nervous systemcerebral ventriclesmeningeal carcinomatosiscytogenetic abnormality
collection DOAJ
language English
format Article
sources DOAJ
author Jung Eun Lee
Eun Ja Lee
Hee Jin Huh
Jae-Woo Chung
Eun Kyoung Lee
Hyun Jung Lee
spellingShingle Jung Eun Lee
Eun Ja Lee
Hee Jin Huh
Jae-Woo Chung
Eun Kyoung Lee
Hyun Jung Lee
Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
대한영상의학회지
multiple myeloma
central nervous system
cerebral ventricles
meningeal carcinomatosis
cytogenetic abnormality
author_facet Jung Eun Lee
Eun Ja Lee
Hee Jin Huh
Jae-Woo Chung
Eun Kyoung Lee
Hyun Jung Lee
author_sort Jung Eun Lee
title Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
title_short Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
title_full Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
title_fullStr Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
title_full_unstemmed Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread
title_sort central nervous system involvement in a patient with multiple myeloma manifesting as an intraventricular mass with leptomeningeal spread
publisher The Korean Society of Radiology
series 대한영상의학회지
issn 1738-2637
2288-2928
publishDate 2018-07-01
description Central nervous system involvement in multiple myeloma (CNS-MM) is a rare condition. Various manifestations of CNS-MM have been reported, including dural, parenchymal, and leptomeningeal involvement. Among them, leptomeningeal involvement is less common and intraventricular involvement is exceptional, with only one case reported in the literature. Herein, we report the first case of CNS-MM manifesting as an intraventricular mass with leptomeningeal involvement combined with perineural spread. We also describe characteristic computed tomography and magnetic resonance imaging findings of intraventricular multiple myeloma.
topic multiple myeloma
central nervous system
cerebral ventricles
meningeal carcinomatosis
cytogenetic abnormality
url https://doi.org/10.3348/jksr.2018.79.1.50
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